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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacteroides abscessus subsp. bolletii 50594
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:MASS_1425Imported
OrganismiMycobacteroides abscessus subsp. bolletii 50594Imported
Taxonomic identifieri1303024 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteroides abscessus
Proteomesi
  • UP000013961 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 96Arg_tRNA_synt_NInterPro annotationAdd BLAST90
Domaini432 – 553DALR_1InterPro annotationAdd BLAST122

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 143"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

R4U8Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAVTPADLA DLLRSTATTV LDERGLDTSA LPAVVTVERP RNPEHGDYAT
60 70 80 90 100
NVALQVAKKV GVAPRDLAGW LVEALVSNAA IAGAEIAGPG FVNLRIAADA
110 120 130 140 150
QGTIVANILK AGETYGNSDA QGTHTINLEF VSANPTGPIH IGGTRWAAVG
160 170 180 190 200
DALGRLLARQ GAKVTREYYF NDHGAQIDRF VRSLIASAEG KEAPEDGYAG
210 220 230 240 250
DYIADIAKQV ITQRPEALSL TEPERSEVFR EIGVDLMFTH IKESLHEFGT
260 270 280 290 300
DFDVFTHEDS MHTSGRVQEA IAQLRKTGNI YEKDGASWLR SSNFGDDKDR
310 320 330 340 350
VVIKSDGNPA YIAGDIAYYL DKRERGFDLC IYMLGADHHG YIARLKAVAA
360 370 380 390 400
ALGYDADSVE VLIGQMVNLV RDGQPVRMSK RAGTVITLDD LVDAIGVDAA
410 420 430 440 450
RYALIRSSVD TSIDIDLELW ASASSENPVY YVQYAHARLC ALARNAADLG
460 470 480 490 500
LQHSTEHLEL LTHEKEGALI RGLGEFGRIL QNAAVLREPH RVARYLEDIA
510 520 530 540 550
GDYHRFYDSC RVLPQGDETP GDLHAARLAL CLATRQVIAN GLDILGVSAP

ERM
Length:553
Mass (Da):59,953
Last modified:July 24, 2013 - v1
Checksum:iA65D5E3129C0D80D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004374 Genomic DNA Translation: AGM28027.1

Genome annotation databases

EnsemblBacteriaiAGM28027; AGM28027; MASS_1425
KEGGimabb:MASS_1425
PATRICifig|1303024.3.peg.1493

Similar proteinsi

Entry informationi

Entry nameiR4U8Q2_9MYCO
AccessioniPrimary (citable) accession number: R4U8Q2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2013
Last sequence update: July 24, 2013
Last modified: June 20, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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