Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Agamous-like MADS-box protein AGL16

Gene

AGL16

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transcription factor involved in the regulation of flowering time in long-day photoperiod. Participates in the repression of FT expression and floral transition, by interacting closely with the FLC-SVP pathways (PubMed:24876250). Functions in the satellite meristemoid lineage of stomatal development (PubMed:17704216).2 Publications

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR
  • protein homodimerization activity Source: UniProtKB
  • RNA polymerase II regulatory region sequence-specific DNA binding Source: InterPro
  • transcription factor binding Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processFlowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Agamous-like MADS-box protein AGL16
Gene namesi
Name:AGL16
Ordered Locus Names:At3g57230
ORF Names:F28O9.80
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G57230
TAIRilocus:2082618 AT3G57230

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004125301 – 240Agamous-like MADS-box protein AGL16Add BLAST240

Proteomic databases

PaxDbiA2RVQ5

Expressioni

Tissue specificityi

Expressed at high levels in leaves, moderate levels in roots, seedlings and stems, and at low levels in flowers, pollen and siliques. Accumulates in leaf guard cells and trichomes. Also present in epidermal cells of roots (PubMed:11115127, PubMed:12837945, PubMed:12949148). Expressed in mature guard cells (PubMed:17704216).4 Publications

Inductioni

Repressed by the micro RNA miR824.1 Publication

Gene expression databases

ExpressionAtlasiA2RVQ5 baseline and differential
GenevisibleiA2RVQ5 AT

Interactioni

Subunit structurei

Homodimer. Interacts with AGL15, AGL24, AP1, AGL6, AG, AGL1, AGL11, AGL5, SEP3, SEP1, AGL63, AGL14, SOC1 and AGL21 (PubMed:15805477). Interacts with AGL63 (PubMed:20598091). Interacts with SVP (PubMed:24876250).3 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
AGL21Q9SZJ65EBI-621930,EBI-621986

GO - Molecular functioni

  • protein homodimerization activity Source: UniProtKB
  • transcription factor binding Source: UniProtKB

Protein-protein interaction databases

BioGridi10206, 23 interactors
IntActiA2RVQ5, 40 interactors
STRINGi3702.AT3G57230.1

Structurei

3D structure databases

ProteinModelPortaliA2RVQ5
SMRiA2RVQ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61MADS-boxPROSITE-ProRule annotationAdd BLAST61
Domaini86 – 176K-boxPROSITE-ProRule annotationAdd BLAST91

Phylogenomic databases

eggNOGiKOG0014 Eukaryota
COG5068 LUCA
HOGENOMiHOG000155301
InParanoidiA2RVQ5
OMAiASEIQFW
OrthoDBiEOG09360MHP
PhylomeDBiA2RVQ5

Family and domain databases

CDDicd00265 MADS_MEF2_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033896 MADS_MEF2-like
IPR002487 TF_Kbox
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF01486 K-box, 1 hit
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS51297 K_BOX, 1 hit
PS00350 MADS_BOX_1, 1 hit
PS50066 MADS_BOX_2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: A2RVQ5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGRGKIAIKR INNSTSRQVT FSKRRNGLLK KAKELAILCD AEVGVIIFSS
60 70 80 90 100
TGRLYDFSSS SMKSVIERYS DAKGETSSEN DPASEIQFWQ KEAAILKRQL
110 120 130 140 150
HNLQENHRQM MGEELSGLSV EALQNLENQL ELSLRGVRMK KDQMLIEEIQ
160 170 180 190 200
VLNREGNLVH QENLDLHKKV NLMHQQNMEL HEKVSEVEGV KIANKNSLLT
210 220 230 240
NGLDMRDTSN EHVHLQLSQP QHDHETHSKA IQLNYFSFIA
Length:240
Mass (Da):27,428
Last modified:March 6, 2007 - v1
Checksum:i96DDECC135221A3B
GO
Isoform 2 (identifier: A2RVQ5-2) [UniParc]FASTAAdd to basket
Also known as: AGL16-II

The sequence of this isoform differs from the canonical sequence as follows:
     142-240: DQMLIEEIQV...IQLNYFSFIA → VLML

Show »
Length:145
Mass (Da):16,388
Checksum:i2B12ADE2FD115F62
GO

Sequence cautioni

The sequence CAB68129 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_041688142 – 240DQMLI…FSFIA → VLML in isoform 2. 1 PublicationAdd BLAST99

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY141209 mRNA Translation: AAN52773.1
AL137080 Genomic DNA Translation: CAB68129.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE79629.1
CP002686 Genomic DNA Translation: AEE79630.2
CP002686 Genomic DNA Translation: ANM64245.1
BT030046 mRNA Translation: ABN04784.1
AF312662 mRNA Translation: AAG37899.1
RefSeqiNP_001319775.1, NM_001339845.1 [A2RVQ5-2]
NP_001326287.1, NM_001339847.1 [A2RVQ5-1]
NP_191282.2, NM_115583.6 [A2RVQ5-1]
UniGeneiAt.21102

Genome annotation databases

EnsemblPlantsiAT3G57230.1; AT3G57230.1; AT3G57230 [A2RVQ5-1]
AT3G57230.2; AT3G57230.2; AT3G57230 [A2RVQ5-2]
AT3G57230.4; AT3G57230.4; AT3G57230 [A2RVQ5-1]
GeneIDi824890
GrameneiAT3G57230.1; AT3G57230.1; AT3G57230 [A2RVQ5-1]
AT3G57230.2; AT3G57230.2; AT3G57230 [A2RVQ5-2]
AT3G57230.4; AT3G57230.4; AT3G57230 [A2RVQ5-1]
KEGGiath:AT3G57230

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiAGL16_ARATH
AccessioniPrimary (citable) accession number: A2RVQ5
Secondary accession number(s): Q7XYY8, Q9FPP0, Q9M2M4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: March 6, 2007
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health